This report by the Institute of Public Policy Research sets out five powerful trends that will drive change in the 2020s. These include: (1) A demographic tipping point: as the population grows, the UK is set to age sharply and become increasingly diverse. (2) An economic world transformed: the economic world order will become more fragile as globalisation evolves, trade patterns shift, and economic power gravitates toward Asia. (3) Brexit - the aftershock: the economic implications of Brexit are likely to put the country on a lower growth, lower investment trajectory, worsening the public finances, with important consequences for the UK's economy and living standards. (4) Technological transformation: exponential improvements in new technologies - computing power, machine learning, artificial intelligence systems, automation, and the Internet of Things - are expected to radically transform social and economic life, with the potential to create an era of widespread abundance, or a second machine age that radically concentrates economic power. (5) The shock of the Anthropocene: climate change and the natural constraints of the Anthropocene age will force us to build a collective, democratic politics of restraint, or alternatively, a system of systemic degradation in ecosystems and rising inequalities in the years ahead. The report emphasises the radical disruption of the coming decades should be met with new institutional solutions which require rethinking notions of work, value and how they connect to identity and culture.