This report by KPMG, the All-Party Parliamentary Group on AI and the Big Innovation Centre serves as a guide for those looking to adapt to the future of work and takes a look at the skills needed to carry out the jobs of the future. It explores AI's impact on skills through two dimensions: (1) AI's impact on what skills individuals should seek to build and policymakers should aim to incentivise; and (2) AI's impact on how these skills are developed, exploring how AI technologies can potentially serve as a tool to build and encourage skills fit for the 21st century. The report concludes that in a world that is uncertain and constantly transforming, the most important skill to have is that of learning to learn.